For the concave spine lesions, intensity modulation was required to provide adequate conformality hence, only IMRT plans were evaluated using either the standard or small leaf-width collimators. For brain and liver lesions, treatment plans using a 3D-conformal static technique (3D), dynamic conformal arcs (DARC) or intensity modulation (IMRT) were designed with a conventional linear accelerator with standard 5 mm leaf width multi-leaf collimator, and a linear accelerator dedicated for radiosurgery and hypofractionated therapy with a 2.5 mm leaf width collimator. All lesions either abutted or were an integral part of critical structures (brainstem, liver or spinal cord). ![]() ![]() Methods Fifteen cases (5 for each site) were studied retrospectively. Specifically, this study evaluated the dosimetric benefits of various techniques and collimator leaf sizes as a function of lesion size and shape. These lesions often present challenges in maximizing dose to target volumes without exceeding critical organ tolerance. ![]() Background This study evaluated the dosimetric impact of various treatment techniques as well as collimator leaf width (2.5 vs 5 mm) for three groups of tumors – spine tumors, brain tumors abutting the brainstem, and liver tumors.
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